BioAssay Research Team

BIOTEC

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Bioassay Research Team

The Bioassay Research Team is a part of the Biosensing and Bioprospecting Technology Research Group at the National Center for Genetic Engineering and Biotechnology (BIOTEC) under the National Science and Technology Development Agency (NSTDA). One of our main purposes is the discovery of microbial natural products that have potential for the development of biological controls against plant pathogens using the combination of biological screening, chemical de-replication based on LC-MS analysis and genome mining approaches. Our research interest also extends to the search for microbial strains that possess the antagonistic activities against plant pathogens and assess their in vivo efficacy to pave the way for the development of the biological control agents for field applications. In addition, our research team has developed the capability to analyze bioactive lipids, such as eicosanoids and polyunsaturated fatty acids (PUFAs), which are known to regulate several physiological systems in crustaceans. Our goal is to understand their roles in shrimp reproductive development and responses against pathogenic infections, with the long-term goals to develop maturation diets for male and female broodstock as well as diets that enhance shrimp immune system during pathogenic infection.

– Platform for the screening of bioactive natural products from microorganisms based on high-throughput anti-microbial assays and LC-HRMS/MS based chemical screening

– Platform technology for quantitative analysis of PUFAs and eicosanoids using LC-HRMS/MS